449-TMEM63A regulates myelin sheath geometry

This research investigates how oligodendrocytes sense and respond to the physical dimensions of the axons they wrap in myelin. The study identifies TMEM63A as a critical mechanosensitive ion channel that allows these cells to convert mechanical pressure into calcium signaling during development. Through experiments with knockout mice and zebrafish, the authors demonstrate that a lack of this chann...去小宇宙查看完整单集简介
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