453-Fatty Acid Recognition by Olfactory Receptors

This research article describes the structural basis and activation mechanism of class II olfactory receptors, specifically focusing on Olfr110. By utilizing cryo-electron microscopy, the authors identified a large, hydrophobic binding pocket that allows these receptors to detect unsaturated fatty acid metabolites like PL45 and 12(S)-HEPE. The study reveals a dual-pocket architecture and a special...去小宇宙查看完整单集简介
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