455-EBV and HLA-DR15 Synergism in Sclerosis Pathogenesis

This research study investigates how the Epstein-Barr virus (EBV) and the HLA-DR15 genetic haplotype work together to trigger multiple sclerosis (MS). The authors demonstrate that EBV infection fundamentally reprograms B cells, causing them to present specific myelin basic protein (MBP) peptides that are typically hidden from the immune system. These viral-induced changes lead to the activation of...去小宇宙查看完整单集简介
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