474-p53 Inactivation in Breast Cancer Metastasis

This research explores how the inactivation of the p53 tumor-suppressor gene significantly increases the likelihood of breast cancer spreading to the brain. While mutations and chromosomal losses in p53 are common in many cancers, this study identifies a specific link to brain metastasis through the reprogramming of fatty acid metabolism. Scientists discovered that p53-deficient cells thrive in th...去小宇宙查看完整单集简介
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