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484-Metabolic Restoration of Stem Cell Fitness

18 min•7 februari 2026
Hematopoietic stem cell (HSC) fitness declines as divisions accrue, shifting BCAA usage from catabolic to anabolic activity. This metabolic drift accelerates the cell cycle and causes lineage infidelity. Supplementing with the metabolite aKIC restores balanced output and regeneration.
References:
* Bartram J, Treichel S, Song B A, et al. Activation of a branched-chain amino acid rheostat restores ...去小宇宙查看完整单集简介
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