489-MYRF: Regulator of Lung Mesothelium Fate and Plasticity

Luna et al. found that Myrf is essential for mesothelium function and lung development. Deleting Myrf causes lung hypoplasia and congenital diaphragmatic hernia (CDH). Without Myrf and Yap/Taz, mesothelial cells transform into ectopic smooth muscle, mimicking adult PPFE.
References:
* Luna G, Verheyden J M, Tan C, et al. MYRF controls mesothelium specification, signaling, and plasticity in lung de...去小宇宙查看完整单集简介
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