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510-Spatial Map of Esophageal Carcinogenesis

15 min•16 februari 2026
High-resolution spatial transcriptomics reveals that JAG1-NOTCH1 signaling drives the formation of a CAF-Epi niche during esophageal cancer progression. This niche triggers ECM remodeling and creates an immune-suppressive barrier, facilitating tumor evasion and poor prognosis.
References:
* Chang J, Lu J, Liu Q, et al. Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis[J]...去小宇宙查看完整单集简介
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