533-SLC45A1 Loss and the Neural Lysosomal Proteome Landscape

Researchers developed a cell-type-specific lysosomal atlas of the brain using LysoIP and proteomics. They identified SLC45A1 as a critical lysosomal glucose transporter in neurons. Its absence impairs lysosomal acidity, V-ATPase assembly, and metabolic recycling, linked to disease.
References:
* Ghoochani A, Heiby J C, Rawat E S, et al. Cell-type resolved protein atlas of brain lysosomes identifie...去小宇宙查看完整单集简介
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