544-Spatial Metastatic Tolerance in Lymph Node Niches

This research explores how cancer spreads to lymph nodes and actively reshapes the immune system to favor tumor growth. By utilizing high-dimensional spatial imaging and transcriptomics on human and mouse tissues, the authors demonstrate that lymph node colonization is not a passive event but a driver of systemic immunosuppression. The presence of tumor cells triggers the formation of suppressive ...去小宇宙查看完整单集简介
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