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551-IGSF11-VISTA: A Targetable Immune Axis

14 min•25 februari 2026
This research identifies IGSF11-VISTA as a critical immune checkpoint axis that governs the unique microenvironment of diffuse midline glioma (DMG). Scientists discovered three distinct spatial niches within these tumors, noting that brain-resident microglia remain in a passive, homeostatic state in regions following developmental programs. Experimental data shows that silencing the Igsf11 gene tr...去小宇宙查看完整单集简介
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