564-Sensory Neurons Drive Immune Exclusion in Breast Cancer

This research investigates how perineural invasion (PNI) serves as a critical driver of treatment resistance in triple-negative breast cancer (TNBC). The studies reveal that sensory neurons within the tumor microenvironment release a signaling molecule called CGRP, which interacts with fibroblasts to promote excessive collagen deposition. This structural reorganization creates a physical barrier t...去小宇宙查看完整单集简介
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