637-Epigenetic Reprogramming of Medulloblastoma Metastasis

This research identifies SMARCD3 as a critical epigenetic driver of medulloblastoma metastasis, particularly in the aggressive Group 3 subgroup. Scientists discovered that this protein hijacks a natural neurodevelopmental program—normally used for Purkinje cell migration in the cerebellum—to help cancer cells spread to the brain and spine. By orchestrating chromatin accessibility at specific regul...去小宇宙查看完整单集简介
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