639-Rhombic Lip Origins of Group 3 and 4 Medulloblastoma

This research paper identifies the rhombic lip (RL) as the unified developmental origin for group 3 and group 4 medulloblastoma, the most clinically challenging subtypes of childhood brain tumors. By utilizing multi-omic mapping and a single-cell transcriptional atlas of the human fetal cerebellum, the authors demonstrate that these tumors mimic the molecular trajectories of early glutamatergic pr...去小宇宙查看完整单集简介
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