647-Monod: Biophysical Modeling of Transcriptional Dynamics

The paper introduce Monod, a Python-based computational framework designed to analyze single-cell RNA sequencing data through the lens of biophysical models. Unlike standard methods that rely on heuristic normalization and dimensionality reduction, Monod fits stochastic models of transcription to nascent and mature RNA counts to distinguish between biological signal and technical noise. This appro...去小宇宙查看完整单集简介
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