660-Stem Cell Engineering of A10 Dopamine Neurons

This research article introduces a novel differentiation protocol designed to generate A10-like midbrain dopaminergic neurons from human pluripotent stem cells. The authors discovered that inhibiting Notch signaling during a specific post-mitotic stage effectively drives the specification of the A10 subtype, which is typically associated with the ventral tegmental area. When transplanted into mice...去小宇宙查看完整单集简介
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