665-CRTAM as a T Cell Checkpoint for Immunotherapy Toxicity

This research identifies CRTAM as a critical immune-related adverse event (irAE) checkpoint that governs the balance between immunotherapy efficacy and side effects. By analyzing patient data and mouse models, the authors discovered that CRTAM+ T cells drive inflammatory toxicity in normal organs like the lungs and colon without significantly affecting antitumor immunity. This specific toxicity oc...去小宇宙查看完整单集简介
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