674-NF-κB Control Prostate Stem Cell Plasticity

This research article examines how Pten deletion triggers the transformation of adult prostate basal cells into multi-lineage stem cells, leading to the initiation of invasive tumors. Through techniques like single-cell RNA sequencing, the authors discovered that this cellular plasticity occurs primarily in specific prostate regions and is driven by the activation of innate immunity and the NF-κB ...去小宇宙查看完整单集简介
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