701-Redefining Targetable CD70 Expression with HIT T Cells

This paper describe a breakthrough in cancer immunotherapy addressing why CAR T cells often fail to eliminate solid tumors. Research reveals that many tumors appearing to be CD70-negative actually possess ultralow levels of the antigen that are hidden by epigenetic silencing via the protein EZH2. To overcome this, scientists engineered a more sensitive HLA-independent T cell (HIT) receptor capable...去小宇宙查看完整单集简介
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