704-STING–NF-κB builds an influenza spillover barrier

This research identifies the STING–NF-κB–GADD34 signaling pathway as a critical innate immune barrier that restricts the transmission of avian influenza A viruses into humans. While the STING protein is well-known for triggering interferons, this study reveals that it also activates an IRF3-independent antiviral response through a specific Gly90 residue. This activation induces the expression of G...去小宇宙查看完整单集简介
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