718-SelO Regulates Mitochondrial Homeostasis

This research identifies SelO as a conserved mitochondrial enzyme that regulates energy metabolism by hydrolyzing NAD+ into NMN and AMP. Using structural analysis of the bacterial homolog ydiU, scientists discovered that this activity is driven by a unique C-terminal selenocysteine residue and is triggered by increases in mitochondrial pH. The study demonstrates that SelO directly associates with ...去小宇宙查看完整单集简介
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