719-OXGR1: A Therapeutic Switch for Rosacea Erythema

Researchers have identified α-KG as a key metabolite that naturally combats the pathological vasodilation and erythema associated with rosacea. By activating the OXGR1 receptor in vascular smooth muscle cells, this metabolite triggers a signaling axis that promotes vasoconstriction and reduces skin redness. Detailed cryo-EM imaging revealed a unique bipartite-acid pocket within the receptor, expla...去小宇宙查看完整单集简介
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