724-Ferritin Aggregation Cell Engagers for CAR T Avidity

This research introduces a novel ferritin aggregation cell engager (FACE) designed to enhance CAR T cell therapy for patients with refractory leukemias. By utilizing the high expression of CD71 receptors on both cancer and therapeutic cells, this platform stabley anchors to CAR T cells to improve their binding strength and sensitivity to low-density antigens. This approach successfully overcomes a...去小宇宙查看完整单集简介
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