729-An Epigenetic Atlas of the Aging Mouse Brain

This study presents a comprehensive single-cell multi-omic atlas of the aging mouse brain across eight distinct regions. By integrating DNA methylation, chromatin conformation, and spatial transcriptomics, the researchers identified 36 major cell types and their specific aging signatures. A key discovery involves the demethylation of transposable elements, which serves as a precise molecular marke...去小宇宙查看完整单集简介
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