732-A Closed Tumor-Immune-Brain Circuit in Cancer Cachexia

This source explores a newly discovered biological circuit involving the tumor, immune system, and brain that drives cancer cachexia, a severe wasting syndrome. Research reveals that pancreatic cancer cells use norepinephrine signaling to recruit macrophages, which then release a protein called GDF15. This protein acts on the hindbrain to trigger a catabolic state, resulting in significant muscle ...去小宇宙查看完整单集简介
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