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Paper Talk

733-Tumor-restraining Fibroblasts Emerge to Chemotherapy

17 min2 april 2026
Recent research has identified a unique subpopulation of cancer-associated fibroblasts (CAFs), known as lipoCAFs, that emerge in bladder cancer patients who respond well to chemotherapy. These specialized cells undergo lipid oxidation reprogramming to produce a signaling molecule called 11-HETE, which effectively boosts the body's immune response against tumors. By inhibiting a specific protein wi...去小宇宙查看完整单集简介
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