739-Dynamic Basis of G-Protein Recognition and Activation

This article describes a study using time-resolved cryo-electron microscopy to visualize the dynamic signaling processes of the human neurotensin receptor type 1 (NTSR1). The researchers captured the receptor in complex with various G-protein subtypes, revealing how the intracellular surface of the receptor reshapes itself to accommodate different partners. By analyzing over 20 intermediate states...去小宇宙查看完整单集简介
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