763-Maf and Jun Regulate Zeb2 to Drive Microglia Development

This research identifies a specialized genetic mechanism that drives microglia development during the earliest stages of life. While most immune cells depend on a specific Zeb2 enhancer for their formation, scientists discovered that microglia and other macrophages from primitive hematopoiesis bypass this requirement. Instead, the transcription factors Maf and Jun activate the Zeb2 gene through a ...去小宇宙查看完整单集简介
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