766-Functional Mapping Mammalian Whole Brain via Perturb-seq

This study introduces a comprehensive functional atlas of the mammalian brain by utilizing an enhanced in vivo Perturb-seq platform to map the effects of 1,947 disease-associated genes. By profiling over 7.7 million individual cells across the mouse brain, researchers identified how genetic loss-of-function impacts specific neuronal populations and transcriptional programs. The findings highlight ...去小宇宙查看完整单集简介
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