788-The MSK-50K Pan-Cancer Resource of Driver Alterations

The paper details the MSK-50K cohort, a massive clinico-genomic study analyzing over 54,000 tumors across 448 cancer subtypes to map tissue-specific driver alterations. Researchers identified 164 new cancer hotspots and discovered that one-third of drivers occur in non-canonical contexts, often displaying unique biological features like increased subclonality and later emergence. The study highlig...去小宇宙查看完整单集简介
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