793-Hypoxia-TAM Dynamics in Glioblastoma

This research identifies a specialized group of monocyte-derived tumor-associated macrophages (Mo-TAMs), termed Hypoxia-TAMs, which congregate in the necrotic regions of glioblastoma. Using single-cell transcriptomics and spatial analysis, the authors discovered that these cells are reprogrammed by the tumor's oxygen-depleted environment to secrete adrenomedullin (ADM). This protein destabilizes v...去小宇宙查看完整单集简介
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