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Paper Talk

801-Landscape of Structural Variation in Pediatric Cancer

24 min16 april 2026
This study in Cancer Cell provides a comprehensive structural variant (SV) map of pediatric cancer by analyzing genomes from 1,616 children and comparing them to adult data. Researchers discovered that while children generally have fewer genomic rearrangements in solid and brain tumors, their blood cancers exhibit a mutational burden similar to adults. A major finding identifies RAG-mediated mutag...去小宇宙查看完整单集简介
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