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Paper Talk

807-Multitissue Epigenomic Variation of Human Disease

24 min17 april 2026
Researchers profiled epigenomic variation across hundreds of human tissue samples to understand how noncoding genetic variants influence complex diseases. By mapping H3K27ac histone marks in the brain, heart, muscle, and lung, the study identified over 280,000 active regulatory elements and linked them to specific biological contexts like sex and tissue type. The authors introduced haQTLs to revea...去小宇宙查看完整单集简介
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