811-ATF4 Regulates DNA Repair in CUX2 Neuron Expansion

This paper explores how the protein ATF4 serves as a vital protector of genome stability during the development of the mammalian brain. The study identifies that CUX2+ neurons, which occupy the upper layers of the cerebral cortex, are uniquely dependent on this factor to manage the stress of rapid cell replication. By utilizing conditional-knockout mice, the authors demonstrate that a lack of ATF4...去小宇宙查看完整单集简介
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