814-Cancer Immunity and the Origins of NMDAR Autoimmunity

This research establishes a mechanical link between triple-negative breast cancer (TNBC) and the autoimmune condition anti-NMDA receptor (ANRE) encephalitis. The study demonstrates that when tumors ectopically express NMDAR subunits, they trigger a robust adaptive immune response where germline-encoded B cells undergo affinity maturation to produce high-affinity autoantibodies. While these antibod...去小宇宙查看完整单集简介
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