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Paper Talk

819-Epigenetic Memory of Colitis Promotes Tumour Growth

25 min18 april 2026
This study investigates the epigenetic memory that remains in colonic stem cells long after inflammation from colitis has resolved. Researchers discovered that even when the tissue appears physically healed, stem cells retain a "memory" of the injury through lasting changes in chromatin accessibility and DNA methylation. This process is driven primarily by the AP-1 transcription factor, which stay...去小宇宙查看完整单集简介
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