831-Spatial Tumor Evolution Panorama of Ovarian Cancer

This research outlines a comprehensive spatial tumor evolution panorama of high-grade serous ovarian cancer using the innovative STARLETS framework. By integrating whole-genome sequencing, single-cell RNA-seq, and spatial transcriptomics, the authors illustrate how hypoxia and immune pressure drive a Darwinian selection of malignant clones that eventually metastasize. The study identifies a unique...去小宇宙查看完整单集简介
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