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Paper Talk

852-Overcoming T Cell Tolerance

19 min25 april 2026
This research article describes a novel "TCR turbocharging" pipeline designed to enhance the effectiveness of T cell receptors used in cancer immunotherapy. Scientists focused on a specific receptor, TCR156, which targets a prostate cancer antigen but naturally lacks the strength to eliminate tumors due to immune tolerance. By engineering specialized interactions called catch bonds, which strength...去小宇宙查看完整单集简介
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