869-The Human-Centric Evolution of Drug Discovery NAMs

This paper explores the transformative shift in drug discovery from traditional animal-based modeling toward human-centric New Approach Methodologies (NAMs). This evolution is driven by high clinical failure rates and is supported by updated regulatory frameworks from the FDA and NIH that no longer mandate animal testing. The review categorizes these innovations into stem cell-based, organoid-base...去小宇宙查看完整单集简介
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