873-Multimodal Mapping of Neocortical Lineage Specification

This research describes how coordinated molecular layers govern brain development in the mouse neocortex. Scientists integrated single-cell transcriptomics and chromatin accessibility with 3D genome architecture and DNA methylation to map how cells decide their identities. A major finding is the identification of thousands of cell-type-specific enhancers, where accessibility often precedes actual ...去小宇宙查看完整单集简介
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