901-Oncofetal Plasticity in Early Colorectal Cancer

This research identifies that metastasis-associated oncofetal cell states emerge at the earliest stages of colorectal cancer, specifically at the invasive front. By utilizing multiregional organoid models and whole-genome sequencing, scientists demonstrated that these aggressive traits are not caused by internal genetic mutations but are instead triggered by the tumour microenvironment. High-resol...去小宇宙查看完整单集简介
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