906-Dual-Engram Control of Alcohol Relapse in dMSNs

This research reveals that opposing alcohol-related memories are stored in distinct neuronal groups, called engrams, within the same cell type in the mouse brain. While acquisition-recruited ensembles promote alcohol relapse, extinction-recruited ensembles work to suppress it by inhibiting dopamine neurons. These two groups are anatomically separated within the dorsomedial striatum, with extinctio...去小宇宙查看完整单集简介
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