913-Brainstem Circuits Driving Opioid Placebo Analgesia

This research identifies a cortical-brainstem circuit that enables the placebo effect to suppress pain in mice. By reverse-translating human conditioning paradigms, the study demonstrates that placebo analgesia requires the release of endogenous opioids within the ventrolateral periaqueductal gray (vlPAG). While both morphine and placebo responses utilize the same descending brainstem pathway, the...去小宇宙查看完整单集简介
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