923-A Tumor-Driven Collapse of Systemic Homeostasis

This paper outlines a systemic framework for understanding cancer cachexia, defining it as a tumor-driven collapse of whole-body homeostasis rather than a simple byproduct of malnutrition. It explains how malignancies function as signaling hubs, releasing a complex secretome of cytokines and vesicles that reprogram the host’s metabolic, immune, and neuroendocrine systems. This process triggers a m...去小宇宙查看完整单集简介
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