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Paper Talk

968-White Matter Lesions Drive Grey Matter Inflammation

21 min14 maj 2026
This study explores how focal white matter lesions act as primary drivers of grey matter inflammation and synaptic loss, rather than being secondary symptoms of neurodegeneration. Using an anatomically precise olivocerebellar circuit model, researchers demonstrated that demyelination triggers a transient adaptive response involving reduced neuronal activity and microglial activation around cell bo...去小宇宙查看完整单集简介
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