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Paper Talk

976-Microtubule Architecture in YAP/TAZ Mechanotransduction

21 min16 maj 2026
This research identifies microtubule architecture as a central regulator of cellular mechanotransduction, specifically influencing the YAP/TAZ signaling pathway. The study demonstrates that mechanical forces cause microtubules to reorganize from a cage-like structure into a radial array centered at the nucleus. This shift facilitates the degradation of AMOT, a protein that acts as a mechanical rhe...去小宇宙查看完整单集简介
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