984-Restrictions of Cell Competition in Mosaic Gastruloids

This research utilizes mouse gastruloids as a three-dimensional model to investigate cell competition during early mammalian development. By introducing p53-deficient supercompetitor cells into wild-type populations, the authors demonstrate that even a tiny fraction of these aggressive cells can trigger mitochondrial apoptosis in their neighbors. The study identifies a specific temporal window—the...去小宇宙查看完整单集简介
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