291. The GLP-1 Side Effect Nobody Warns You About

You might think the win on a GLP-1 like Ozempic or Mounjaro is the number dropping on your scale, but I need you to ask a better question, not how much you're losing, but what kind. In some studies, 40 to 60% of the weight people lost on these drugs came from lean muscle, not fat, and that's a metabolic loss that costs you your strength and your ability to keep the weight off. These are the most powerful fat-loss tools we've ever had, but a tool without a protocol is just potential. Hit your protein and lift, or you're trading muscle for a number you'll spend years trying to earn back.

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Timestamps

00:00 - Intro of Show

00:22 - Weight loss vs fat loss

00:38 - What GLP-1 does in the body

01:02 - Semaglutide: the first generation

01:28 - Tirzepatide and the dual agonist

01:45 - Retatrutide and 24.2% body weight loss

02:20 - Why each added receptor works

02:38 - The hidden cost: protecting lean muscle

03:05 - 60% of weight loss from muscle

03:35 - The two-part fix: protein and training

04:05 - Protein targets and leucine-rich sources

04:30 - Resistance training and compound lifts

05:00 - Use the medication, do the work

Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. 

Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation.  Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature.

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