TWiV 1333: STING like a nanoparticle, float like HIV

TWiV explains research showing how HIV-1 signalling remodels nuclear pores to licence infection, and development of STING agonist nanoparticles to enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection.

Hosts: VVincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Links for this episode

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• Bundibugyo ebolavirus sitrep (WHO)
• Ebolavirus and Andes virus with John Dye (TWiV Special)
• Major research nonhuman primate supplier going out of business (Science)
• HIV-1 signalling remodels nuclear pores to licence infection (Nature)
• STING agonist nanoparticles enable mucosal-systemic immunity (Nature Nanoparticles)
• Timestamps by Jolene Ramsey. Thanks!

Picks of the Week

Brianne – Otherworldly music albums feature space weather data Rich – Evidence Mapping: Consolidating and summarising available evidence to support the demonstration of effectiveness of developmental vaccines, Australian Living Evidence Collaboration (ALEC) Alan – Holyoke dam fish elevator Vincent – 68 Quadrillion Underground Miles of Fungi

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.