TWiV 1353: Phage bet-hedging and EBV antibodies

TWiV explores how bacteriophages enable bet-hedge against bacterial immune defenses, and how transgenic mice engineered to produce human antibodies yielded potent anti-EBV candidates targeting gp350 and gp42, a promising step toward Epstein-Barr therapeutics.

Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey

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Links for this episode

• Support science education at MicrobeTV
• Dolly Parton, and advocate for science (Nature)
• Phage bet-hedging (Nat Micro)
• EBV monoclonal antibodies (Cell Rep Med)
• Letters read on TWiV 1353
• Timestamps by Jolene Ramsey. Thanks!

Picks of the Week

Brianne – Did life on Earth emerge once or twice? Rich – Cassini Approaches Saturn (Wiki on Cassini) Jolene – Dolly Parton’s rewrite of Jolene song for vaccines on CBS news (Youtube) Vincent – Thinking, Fast and Slow by Daniel Kahneman

Listener Pick

John – Dolly Parton Sings Vaccine, Vaccine

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.