TWiV 1357: Furin, Naturally with Paul Bieniasz
Om avsnittet
Paul Bieniasz joins TWiV to discuss his lab’s discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the viral RNA, generating insertion mutations at a frequency above 10⁻³ per genome, including new furin cleavage sites at the spike S1/S2 junction.
Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Guest: Paul BieniaszSubscribe (free): Apple Podcasts, RSS, email
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Links for this episode- Support science education at MicrobeTV
- Genetic innovation in coronaviruses driven by a viral nuclease (bioRxiv)
- Letters read on TWiV 1357
- Timestamps by Jolene Ramsey. Thanks!
Kathy – Jurassic Museum of Asturias Alan – Grand Central Winter, by Lee Stringer Vincent – How to Choose REAL Extra Virgin Olive Oil: A Practical Guide and How to Tell if Your Olive Oil is Fake! Quick Kitchen Tip!
Listener PickShirley – I Told You So! by Matt Kaplan
Intro music is by Ronald Jenkees
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Content in this podcast should not be construed as medical advice.
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